Following the research in most reports, Follistatin 344 is a myostatin inhibitor. Myostatin is the hormone created by the body that limits the amount of muscle it builds. In studies conducted with mice, there were no observed effects on their organs, reproductive capabilities, or FSH levels. Follistatin was also able to improve muscle and motor function in mice from another research report. In that case the mice had suffered from spinal atrophy prior to administration of Follistatin 344.
| Application: | Myostatin inhibitor |
| CAS: | 117628-82-7 |
| Molecular Weight: | 3780 g·mol |
| Chemical Formula: | N/A |
| Chemical Name: | Recombinant Human Follistatin |
| Synonyms: | FS-344, Follistatin |
| Storage: | Minimize open air exposure, store in a cool dry place. |
| Stability: | 2 years |
| Purity: | >99-99.9% |
| Solubility: | Soluble to water at rate of 0.1mg/mL |
| Physical Form: | fine powder in glass vial |
| Specifications: | 1mg vial |
| Terms: | The products we offer are intended for laboratory research use only. You will need to purchase Bacteriostatic water separately. |
Structure of Follistatin 344
Follistatin 344 is a glycoprotein encoded by the FST gene, known for its role in regulating the activity of myostatin, a protein that inhibits muscle growth. Structurally, Follistatin 344 consists of a sequence of amino acids, specifically residues 29 to 344, which form its primary structure. Additionally, Follistatin contains carbohydrate chains attached to its amino acid backbone, contributing to its stability and solubility in biological fluids.
The protein contains multiple domains, including the follistatin domain, which is crucial for its inhibitory activity against myostatin. Within this domain, specific regions facilitate the direct interaction between Follistatin 344 and myostatin, preventing myostatin from exerting its negative effects on muscle growth.
Understanding the structural features of Follistatin 344 is essential for elucidating its mechanisms of action and potential therapeutic applications, particularly in the field of muscle biology and tissue regeneration.
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