OTHER KNOWN TITLES: Acetyl Glutamyl Heptapeptide-3
MOLECULAR FORMULA: C41H70N16O16S
MOLECULAR WEIGHT: 1075.16 g/mol
SEQUENCE: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2
SNAP-8 AND WRINKLE DEPTH
Research studies have suggested SNAP-8 may exhibit reduction capacity in the depth of wrinkles along the skin surface due to a possible resistance to contraction of the muscles. Some studies have suggested peptide exposure may lead to a decrease in wrinkle depth by as much as 30% with studies reporting SNAP-8 exposure for only one month.[3] According to the researchers, “it is also worth to be remarked that in vitro assay highlighted an independent mechanism but synergistic effect between SNAP-8 and Leuphasyl, each one tested independently and resulting with 38% and 7% inhibition, respectively. In the trial, including both of them in equal concentrations (0.75 mM), a total inhibition value of 47% was observed.”
SNAP-8 AND BOTULINUM TOXIN
Botulinum toxin has been extensively studied and is commonly considered to restrict muscle contraction and thereby inhibit wrinkles. SNAP-8 appears to target the same wrinkle-forming mechanism via a differing mechanism of action. Botulinum toxin is considered to attack and break SNAP-25. This may lead to muscle paralysis, inhibiting muscle contraction.[4] SNAP-8 appears to capture the SNAP-25 protein, thereby destabilizing the SNARE complex. This is considered to lead to the inefficient release of neurotransmitters responsible for muscle contraction.[5] According to the researchers the peptide may potentially act by “preventing neuromuscular signal propagation, thereby eliminating wrinkles caused by over-stimulated neurons.”
SNAP-8 AND HYDRATION, ANTI-OXIDATION
Like other comparable peptides, SNAP-8 appears to possess water-binding capacity.[6] Therefore, it may help the extracellular matrix of skin retain moisture. Alongside its possible hydration retaining characteristics, the peptide has been observed to exert protective impact against reactive oxygen species. Reactive oxygen species or free radicals are considered to have a major degenerative effect on skin cells.
Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.
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