• New Product igf  Insulin-like Growth Factor 0.1mg/ 1mg
  • New Product igf  Insulin-like Growth Factor 0.1mg/ 1mg

New Product igf Insulin-like Growth Factor 0.1mg/ 1mg

pro igf 1 with the best quality for sale
  • New Product igf  Insulin-like Growth Factor 0.1mg/ 1mg

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White  Powder







What is the Receptor Grade IGF-1 LR3 Peptide?

RECEPTOR GRADE IGF-1 LR3 is an altered variant of insulin-like growth factor-1; the complete name of the peptide is insulin-like growth factor-1 long arginine 3. IGF-1 derivatives have played important roles in research studies on cell proliferation, cell division, and cell-to-cell communication. Despite showing physiological effects similar to the parent protein, Receptor Grade IGF-1 LR3 does not interact with IGF binding proteins as strongly as IGF-1. Hence, it appears to stay in the bloodstream for longer durations (about 120 times longer) as compared to native IGF-1. The structural modifications in IGF-1 LR3 may have contributed to its increased half-life in the blood. The peptide is created by the inclusion of 13 amino acids to the N-terminus of native IGF-1 and by replacing the glutamic acid at position 3 to arginine.

Like IGF-1, research suggests that Receptor Grade IGF-1 LR3 may act as a stimulus for cell division and proliferation, primarily affecting connective tissues of the muscle and bone and cell division in the liver, kidney, skin, lung, nerve, and blood tissues. IGF-1 is best considered to be a maturation hormone because of its apparent influence in cell proliferation, differentiation, and maturation, helping them to carry out their specialized functions. The longer life span of Receptor Grade IGF-1 LR3 in the blood makes it a more potent molecule as compared to IGF-1. A single dose of Receptor Grade IGF-1 LR3 appears to provide about three times as much cellular activation compared to a similar dose of IGF-1.[2] Researchers report that “The response with LR3IGF-I was particularly striking because this peptide binds 3-fold less well than IGF-I to the type 1 IGF receptor.“ It is important to remember that IGF-1 LR3 peptide and every IGF-1 derivative have not been observed to mediate cellular enlargement (hypertrophy), and instead may participate in cell division and proliferation (hyperplasia). For instance, in the case of muscle, studies suggest Receptor Grade IGF-1 LR3 would not cause enlargement of muscle cells, rather simply increasing the total number of muscle cells.

Myostatin (also known as growth differentiation factor 8) is a muscle protein that primarily suppresses the growth and differentiation of muscle cells. Myostatin is, thus crucial in protection from unregulated hypertrophy and proper healing post-injury. However, some situations that demand inhibition of myosin. Blocking of myosin can be helpful in conditions like Duchenne Muscular Dystrophy (DMD) or in people who suffer from loss of muscle due to prolonged immobility. In such cases, blocking the natural enzyme could help slow down muscle breakdown, maintain strength, and avoid morbidity. Studies conducted in mouse models of DMD have suggested that Receptor Grade IGF-1 LR3 and other IGF-1 derivatives may overcome the adverse effects of Myostatin to protect muscle cells and prevent apoptosis.[3] The scientists note that “results together suggest that myostatin suppresses both basal and IGF-1-stimulated proliferation of both WAT and BAT preadipocytes, actions that are again similar to those in muscle satellite cells”. Receptor Grade IGF-1 LR3, due to its long stability, may be effective in counteracting Myostatin by activating MyoD, a muscle protein that is normally triggered by exercise (e.g., weight lifting).

Researchers suggest that Receptor Grade IGF-1 LR3 indirectly boosts fat burning by associating with the IGF-1R receptor and the insulin receptor. These interactions may improve glucose uptake from the blood by muscle, nerve, and liver cells. This potential would result in an overall reduction in blood sugar levels, which then trigger adipose tissue as well as the liver to initiate catabolism of glycogen and triglycerides. Overall, this leads to a decrease in adipose tissue and net energy consumption (i.e. net catabolism). Given its role in controlling blood sugar levels, Receptor Grade IGF-1 LR3 may reduce insulin levels and the need for exogenous insulin in diabetes.  In a majority of the patients, this brings about a 10% reduction in insulin requirements to maintain the same blood sugar levels.[4] Receptor Grade IGF-1 LR3 thus helps understand insulin regulation in patients with decreased insulin sensitivity. It also highlights possible ways to prevent type 2 diabetes.

Studies observe that Receptor Grade IGF-1 LR3 may promote tissue repair and upkeep of the body, making it a protective molecule against cellular damage and the effects of aging. Research in cows and pigs indicate that Receptor Grade IGF-1 LR3 administration may overcome the effects of aging, prolong life and reduce disability. Ongoing research in mice has focused on the potential of Receptor Grade IGF-1 LR3 in preventing the progression of a wide range of conditions such as muscle atrophy, dementia, and kidney disease.[5]

Glucocorticoids, produced essentially from the adrenal glands, also act as important clinical medications which help to control pain and decrease inflammation in autoimmune diseases, cancer, and neurological injuries, to name a few. However, glucocorticoids have numerous undesirable side effects, such as muscle wasting, fat gain, and deterioration of bone density. Thus, Receptor Grade IGF-1 LR3 is being explored as an option to reduce the side effects of glucocorticoids and thereby mediate a more effective therapy. Studies have shown minimal to moderate side effects, low oral bioavailability, and excellent subcutaneous bioavailability in mice.[6]
Per kg dosage in mice does not scale up to the dosage which can be required for humans.

Our Advantage: 

1. Faster delivery: Sample order in stock and 3-7 days for bulk production.

2. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

3. After-Sale Service: 

1)International Authorized Third-Party Test For The Products You Demand. 

2)60 Days Warranty of quality of goods.


Packing & Shipping:

1.As your requirements.

2. Prompt shipment after receipt of your order confirmation.

3.Transit could be DHL UPS TNT EMS Fedex and so on.

4. For mass orders,it will be delivered by air or sea.

5.Depending on your locationplease allow 1-5 business days for your order to arrive.

6.For small order please expect 3-7 days by UPS DHL EMS

7.For mass order please allow 5-8 days by air 15-30 days by sea.

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About us

WuhanZhengtai Technology Co., Ltd is mainly engaged in the export of fine chemicals, cosmetic raw materials, food additives, pharmaceutical intermediates and other products; Our company is committed to the development of international market, our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. 

Meanwhile, we possess of complete Q. A. And Q. C. System, supply chemical products with good quality and custom-tailored products according to our clients′ requirement. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the 15 years. With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

Our advantages

Quality: Purity above 99%, directly produced by the manufacturer, can accept quality testing, and can also customize any content of powder, liquid, oil, etc. 

Transport: We can accept sea freight, air freight, and express delivery, with a guarantee time of 1-2 weeks and a customs clearance rate of over 99%.

Service: In addition to powder, we also have liquids, water-based agents, oils, tablets, and professional customized synthesis routes. We provide you with professional guidance on product use, product synthesis, and product customization.

Price: We do not engage in price wars. We are manufacturer and can provide high quality products with factory price.


Q: How to start orders or make payments?

A:You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How to confirm the Product Quality before placing orders?

A:You can get samples for some products to test. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q: What's your MOQ?

A:For the high value product, our MOQ starts from 1box.

Q: Is there a discount?

A: Yes, for larger quantity, we always support with better price.

Q:How do you treat quality complaint?

First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.

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