• 99% Purity Raw Powder Dsip CAS 62568-57-4
  • 99% Purity Raw Powder Dsip CAS 62568-57-4

99% Purity Raw Powder Dsip CAS 62568-57-4 Delta Sleep-Inducing Peptide

CAS No.: 62568-57-4 Formula: C35H48N10O15 EINECS: 211-519-9 Type: Pharmaceutical Intermediates Appearance: Powder Quality: Refined
  • 99% Purity Raw Powder Dsip CAS 62568-57-4

What Is DSIP (Delta Sleep-Inducing Peptide)?

DSIP, also known as Delta Sleep-Inducing Peptide, is a neuropeptide first discovered in the 1970s. It is naturally produced in the body and plays a role in regulating sleep patterns.

DSIP is believed to induce deep sleep and promote restful and restorative sleep cycles. It has been studied for its potential therapeutic applications, particularly in treating sleep disorders and related conditions such as insomnia.

Research suggests that DSIP may help regulate the release of other hormones in the body, including melatonin and cortisol, which are important for maintaining a healthy sleep-wake cycle. It is thought to promote the production of delta waves in the brain, which are associated with deep sleep.

DSIP Structure

  • Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
  • Molecular Formula: C35H48N10O15
  • Molecular Weight: 848.824 g/mol
  • PubChem CID: 68816
  • CAS Number: 62568-57-4
  • Synonyms: Emideltide, DSIP nonapeptide, Deltaran

dsip structure

Source: PubChem

The Relationship of DSIP to Sleep

DSIP is a neuropeptide studied for its relationship to sleep. Research suggests that DSIP may play a role in promoting deep and restful sleep.

A review published in PubMed highlights that DSIP induces delta-sleep, which is associated with deep sleep, in rabbits, rats, mice, and humans. However, the effects on cats were found to be different.

Plasma DSIP-like immunoreactivity decreased during the transition from wakefulness to sleep, suggesting a potential link between DSIP and sleep stages.

While some studies suggest a correlation between DSIP and the promotion of slow-wave sleep (SWS) and the suppression of paradoxical sleep (PS), other studies show no clear correlation.

The specific mechanisms and exact role of DSIP in sleep regulation are still not fully understood. There is ongoing research to further characterize the relationship between DSIP and sleep.

DSIP Research and Chronic Pain

While there is limited research specifically focused on DSIP and chronic pain, there are some studies that suggest a possible connection.

One study published in the journal “Pain Medicine” explored the effects of DSIP on patients with chronic pain. The researchers found that DSIP administration improved pain intensity and sleep quality in the participants. However, it’s important to note that this study had a small sample size, and more research is needed to draw definitive conclusions.

Another study published in the journal “Neuroscience Letters” investigated the analgesic (pain-relieving) effects of DSIP in animal models. The results showed that DSIP administration significantly reduced pain sensitivity in rats, suggesting its potential as a pain management tool. Again, further research is needed to ascertain the efficacy and safety of DSIP in humans.

DSIP Research and Metabolism

DSIP, or Delta Sleep-Inducing Peptide, is primarily known for regulating sleep patterns. While research on DSIP and metabolism is limited, some studies suggest a potential link.

One study investigated the effects of DSIP on lipid metabolism in rats. The researchers found that DSIP administration reduced body weight, fat mass, and serum lipid levels in the rats. This suggests that DSIP may have a modulatory effect on lipid metabolism.

Another study explored the influence of DSIP on glucose metabolism in rats. The findings indicated that DSIP administration improved glucose tolerance and insulin sensitivity in the rats, potentially suggesting a role in regulating glucose metabolism.

However, it’s important to note that the research on DSIP and metabolism is still preliminary, and more studies are needed to understand the mechanisms and effects fully. 

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WuhanZhengtai Technology Co., Ltd is mainly engaged in the export of fine chemicals, cosmetic raw materials, food additives, pharmaceutical intermediates and other products; Our company is committed to the development of international market, our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. 

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